Goshajinkigan oxaliplatin neurotoxicity evaluation (GONE): a phase 2, multicenter, randomized, double-blind, placebo-controlled trial of goshajinkigan to prevent oxaliplatin-induced neuropathy

PURPOSE: Oxaliplatin-induced peripheral neurotoxicity (OPN) is frequent and potentially severe, but successful treatment of this condition is still an unmet clinical need. We aimed to determine whether treatment with goshajinkigan (TJ-107), a traditional Japanese medicine, is better than placebo in...

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Autores principales: Kono, Toru, Hata, Taishi, Morita, Satoshi, Munemoto, Yoshinori, Matsui, Takanori, Kojima, Hiroshi, Takemoto, Hiroyoshi, Fukunaga, Mutsumi, Nagata, Naoki, Shimada, Mitsuo, Sakamoto, Junichi, Mishima, Hideyuki
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer Berlin Heidelberg 2013
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834178/
https://ncbi.nlm.nih.gov/pubmed/24121454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-013-2306-7
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