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Mannose receptor (MRC1) mediates cellular uptake and endosomal delivery of CpG-ODN
Recognition of microbial components is critical for activation of Toll-like receptors (TLRs), subsequent innate immune signaling and directing adaptive immune responses. The DNA sensor TLR9 traffics from the endoplasmic reticulum (ER) to endolysosomal compartments where it is cleaved by resident pro...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3834123/ https://ncbi.nlm.nih.gov/pubmed/24184555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301438 |
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