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Genetic and Pharmacokinetic Determinants of Response to Transdermal Nicotine in White, Black and Asian Non-Smokers

The aim of the study was to examine genetic, pharmacokinetic and demographic factors that influence sensitivity to nicotine in never smokers. Sixty never smokers, balanced for gender and race (Caucasian, Blacks and Asian), wore 7 mg nicotine skin patches for up to 8 hours. Serial plasma nicotine con...

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Detalhes bibliográficos
Main Authors: Dempsey, Delia A., St Helen, Gideon, Jacob, Peyton, Tyndale, Rachel F., Benowitz, Neal L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834081/
https://ncbi.nlm.nih.gov/pubmed/23933970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2013.159
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