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PX-12-induced HeLa cell death is associated with oxidative stress and GSH depletion

PX-12, as an inhibitor of thioredoxin (Trx), has antitumor activity. However, little is known about the toxicological effect of PX-12 on cervical cancer cells. In the present study, the growth inhibitory effects of PX-12 on HeLa cervical cancer cells in association with reactive oxygen species (ROS)...

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Hlavní autoři: SHIN, HYE RIM, YOU, BO RA, PARK, WOO HYUN
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3833989/
https://ncbi.nlm.nih.gov/pubmed/24260080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2013.1637
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