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Polyamine depletion is associated with altered chromatin structure in HeLa cells.

HeLa cells depleted of polyamines by treatment with alpha-difluoromethylornithine (DFMO), methylglyoxal bis(guanylhydrazone) (MGBG) or a combination of the two, were examined for sensitivity to micrococcal nuclease, DNAase I and DNAase II. The degrees of chromatin accessibility to DNAase I and II ap...

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Detalhes bibliográficos
Autor principal: Snyder, R D
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1138733/
https://ncbi.nlm.nih.gov/pubmed/2504149
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