Investigation of CBS, MTR, RFC-1 and TC Polymorphisms as Maternal Risk Factors for Down Syndrome

Recent evidence shows that almost 92% of the DS children are born from young mothers, suggesting that other risk factors than advanced maternal age must be involved. In this context, some studies demonstrated a possible link between DS and maternal polymorphisms in genes involved in folate metabolis...

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Main Authors: Fintelman-Rodrigues, N., Corrêa, J. C., Santos, J. M., Pimentel, M. M. G., Santos-Rebouças, C. B.
Format: Artigo
Sprog:Inglês
Udgivet: IOS Press 2009
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3833707/
https://ncbi.nlm.nih.gov/pubmed/19729796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/DMA-2009-0626
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