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Initiation of (-) strand DNA synthesis from tRNA(3Lys) on lentiviral RNAs: implications of specific HIV-1 RNA-tRNA(3Lys) interactions inhibiting primer utilization by retroviral reverse transcriptases.

Initiation of minus (-) strand DNA synthesis was examined on templates containing R, U5, and primer-binding site regions of the human immunodeficiency virus type 1 (HIV-1), feline immunodeficiency virus (FIV), and equine infectious anemia virus (EIAV) genomic RNA. DNA synthesis was initiated from (i...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Arts, E J, Stetor, S R, Li, X, Rausch, J W, Howard, K J, Ehresmann, B, North, T W, Wöhrl, B M, Goody, R S, Wainberg, M A, Grice, S F
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1996
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38336/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8816751/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.19.10063
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