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Structure–function relationships of the initiation complex of HIV-1 reverse transcription: the case of mutant viruses using tRNA(His) as primer

Reverse transcription of HIV-1 RNA is initiated from the 3′ end of a tRNA(3)(Lys) molecule annealed to the primer binding site (PBS). An additional interaction between the anticodon loop of tRNA(3)(Lys) and a viral A-rich loop is required for efficient initiation of reverse transcription of the HIV-...

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Autors principals: Rigourd, Mickaël, Goldschmidt, Valérie, Brulé, Fabienne, Morrow, Casey D., Ehresmann, Bernard, Ehresmann, Chantal, Marquet, Roland
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC206454/
https://ncbi.nlm.nih.gov/pubmed/14500840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg754
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