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The pervasiveness of interleukin-1 in Alzheimer pathogenesis: a role for specific polymorphisms in disease risk

Interleukin-1 (IL-1) has been implicated as a key molecule in Alzheimer pathogenesis based on findings of an IL-1 overexpression in Alzheimer brain that is directly related to plaque progression and tangle formation, and on findings that IL-1 induces excessive synthesis, translation, and processing...

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Hlavní autoři: Griffin, W.S.T., Nicoll, J.A.R., Grimaldi, L.M.E., Sheng, J.G., Mrak, R.E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3833595/
https://ncbi.nlm.nih.gov/pubmed/10959036
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