Antidepressant-like activity of S 20098 (agomelatine) in the forced swimming test in rodents: involvement of melatonin and serotonin receptors

OBJECTIVE: To study agomelatine (S 20098), a potent agonist at melatonin receptors and antagonist at serotonin-2C (5-HT(2C)) receptors, in an animal model of depression, namely, the rodent forced swimming test (FST). METHODS: The effects of acute and repeated administration of S 20098 were compared...

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Hlavní autoři: Bourin, Michel, Mocaër, Elisabeth, Porsolt, Roger
Médium: Artigo
Jazyk:Inglês
Vydáno: 2004
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC383344/
https://ncbi.nlm.nih.gov/pubmed/15069466
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