CDIP1-BAP31 complex transduces apoptotic signals from endoplasmic reticulum to mitochondria under ER stress

Resolved ER stress response is essential for intracellular homeostatic balance, but unsettled ER stress can lead to apoptosis. Here, we show that a pro-apoptotic p53 target, CDIP1, acts as a key signal transducer of ER stress-mediated apoptosis. We identify BAP31, B-cell receptor-associated protein...

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Detalhes bibliográficos
Main Authors: Namba, Takushi, Tian, Fang, Chu, Kiki, Hwang, So-Young, Yoon, Kyoung Wan, Byun, Sanguine, Hiraki, Masatsugu, Mandinova, Anna, Lee, Sam W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3833439/
https://ncbi.nlm.nih.gov/pubmed/24139803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.09.020
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