Differential control of metabolic and cardiovascular functions by melanocortin-4 receptors in proopiomelanocortin neurons

We examined the role of melanocortin-4 receptors (MC4R) in proopiomelanocortin (Pomc) neurons in regulating metabolic and cardiovascular functions. Using Cre-loxP technology, we selectively rescued MC4R in Pomc neurons of mice with whole body MC4R deficiency (MC4R-Pomc-Cre mice). Body weight, food i...

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Bibliographic Details
Main Authors: do Carmo, Jussara M., da Silva, Alexandre A., Rushing, John S., Pace, Benjamin, Hall, John E.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2013
Subjects:
Neural Control
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3833394/
https://ncbi.nlm.nih.gov/pubmed/23842677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00518.2012
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