Cortisol stimulates proliferation and apoptosis in the late gestation fetal heart: differential effects of mineralocorticoid and glucocorticoid receptors

We have previously found that modest chronic increases in maternal cortisol result in an enlarged fetal heart. To explore the mechanisms of this effect, we used intrapericardial infusions of a mineralocorticoid receptor (MR) antagonist (canrenoate) or of a glucocorticoid receptor (GR) antagonist (mi...

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Hlavní autoři: Feng, Xiaodi, Reini, Seth A., Richards, Elaine, Wood, Charles E., Keller-Wood, Maureen
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2013
Témata:
Cardiovascular and Renal Integration
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3833392/
https://ncbi.nlm.nih.gov/pubmed/23785077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00112.2013
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