Cortisol stimulates proliferation and apoptosis in the late gestation fetal heart: differential effects of mineralocorticoid and glucocorticoid receptors

We have previously found that modest chronic increases in maternal cortisol result in an enlarged fetal heart. To explore the mechanisms of this effect, we used intrapericardial infusions of a mineralocorticoid receptor (MR) antagonist (canrenoate) or of a glucocorticoid receptor (GR) antagonist (mi...

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Main Authors: Feng, Xiaodi, Reini, Seth A., Richards, Elaine, Wood, Charles E., Keller-Wood, Maureen
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2013
Assuntos:
Cardiovascular and Renal Integration
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3833392/
https://ncbi.nlm.nih.gov/pubmed/23785077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00112.2013
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