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Synthesis of azide derivative and discovery of glyoxalase pathway inhibitor against pathogenic bacteria(1)
A Glyoxalase inhibitor was synthesized and tested against Staphylococcus aureus for first time and showed MIC(90) of 20 μg/ml. Henceforth, we synthesized unnatural azide derivative of the same inhibitor to improve the biological activity. In that order, an azide carboxylate was synthesized from dime...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3833347/ https://ncbi.nlm.nih.gov/pubmed/24076169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2013.09.011 |
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