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Neuroprotection through flavonoid: Enhancement of the glyoxalase pathway

The glyoxalase pathway functions to detoxify reactive dicarbonyl compounds, most importantly methylglyoxal. The glyoxalase pathway is an antioxidant defense mechanism that is essential for neuroprotection. Excessive concentrations of methylglyoxal have deleterious effects on cells, leading to increa...

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Dades bibliogràfiques
Publicat a:Redox Biol
Autors principals: Frandsen, Joel R., Narayanasamy, Prabagaran
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680520/
https://ncbi.nlm.nih.gov/pubmed/29080525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.10.015
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