Neuroprotection through flavonoid: Enhancement of the glyoxalase pathway

The glyoxalase pathway functions to detoxify reactive dicarbonyl compounds, most importantly methylglyoxal. The glyoxalase pathway is an antioxidant defense mechanism that is essential for neuroprotection. Excessive concentrations of methylglyoxal have deleterious effects on cells, leading to increa...

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Bibliografische gegevens
Gepubliceerd in:Redox Biol
Hoofdauteurs: Frandsen, Joel R., Narayanasamy, Prabagaran
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2017
Onderwerpen:
Short Review
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680520/
https://ncbi.nlm.nih.gov/pubmed/29080525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.10.015
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