In vivo modification of Abeta plaque toxicity as a novel neuroprotective lithium-mediated therapy for Alzheimer’s disease pathology

BACKGROUND: Alzheimer’s disease (AD) is characterized by the abnormal accumulation of extracellular beta-amyloid (Abeta) plaques, intracellular hyperphosphorylated tau, progressive synaptic alterations, axonal dystrophies, neuronal loss and the deterioration of cognitive capabilities of patients. Ho...

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Detalhes bibliográficos
Main Authors: Trujillo-Estrada, Laura, Jimenez, Sebastian, De Castro, Vanessa, Torres, Manuel, Baglietto-Vargas, David, Moreno-Gonzalez, Ines, Navarro, Victoria, Sanchez-Varo, Raquel, Sanchez-Mejias, Elisabeth, Davila, Jose Carlos, Vizuete, Marisa, Gutierrez, Antonia, Vitorica, Javier
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3833287/
https://ncbi.nlm.nih.gov/pubmed/24252759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2051-5960-1-73
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