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Application of An Efficient Gene Targeting System Linking Secondary Metabolites to Their Biosynthetic Genes in Aspergillus terreus
[Image: see text] Nonribosomal peptides (NRPs) are natural products biosynthesized by NRP synthetases. A kusA-, pyrG- mutant strain of Aspergillus terreus NIH 2624 was developed that greatly facilitated the gene targeting efficiency in this organism. Application of this tool allowed us to link four...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3833251/ https://ncbi.nlm.nih.gov/pubmed/23841722 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol401384v |
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