Coronary microvascular pericytes are the cellular target of sunitinib malate induced cardiotoxicity

Sunitinib malate is a multi-targeted receptor tyrosine kinase inhibitor used in the treatment of human malignancies. A substantial number of sunitinib-treated patients develop cardiac dysfunction, but the mechanism of sunitinib-induced cardiotoxicity is poorly understood. We show that mice treated w...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chintalgattu, Vishnu, Rees, Meredith L., Culver, James C., Goel, Aditya, Jiffar, Tilahu, Zhang, Jianhu, Dunner, Kenneth, Pati, Shibani, Bankson, James A., Pasqualini, Renata, Arap, Wadih, Bryan, Nathan S., Taegtmeyer, Heinrich, Langley, Robert R., Yao, Hui, Kupferman, Michael E., Entman, Mark L., Dickinson, Mary E., Khakoo, Aarif Y.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3833098/
https://ncbi.nlm.nih.gov/pubmed/23720580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3005066
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