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Overexpression of TLR7 promotes cell-intrinsic expansion and autoantibody production by transitional T1 B cells
Toll-like receptor (TLR), a ligand for single-stranded RNA, has been implicated in the development of pathogenic anti-RNA autoantibodies both in systemic lupus erythematous (SLE) patients and in murine models of lupus. It is still unclear, however, where and how TLR7-mediated interactions affect the...
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| Główni autorzy: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
The Rockefeller University Press
2013
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3832927/ https://ncbi.nlm.nih.gov/pubmed/24145511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20122798 |
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