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Insulinoma-released exosomes activate autoreactive marginal zone-like B cells that expand endogenously in prediabetic NOD mice
Exosomes (EXOs) are nano-sized secreted microvesicles that can function as potent endogenous carriers of adjuvant and antigens. To examine a possible role in autoimmunity for EXOs, we studied EXO-induced immune responses in non-obese diabetic (NOD) mice, an autoimmune-prone strain with tissue-specif...
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| Główni autorzy: | , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2013
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3832688/ https://ncbi.nlm.nih.gov/pubmed/23817982 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201343376 |
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