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Insulinoma-released exosomes or microparticles are immunostimulatory and can activate autoreactive T cells spontaneously developed in non-obese diabetes mice()

Exosomes (EXO) are secreted intracellular microparticles that can trigger inflammation and induce antigen-specific immune responses. To test possible roles of EXO in autoimmunity, we isolated small microparticles, mainly EXO, from mouse insulinoma and examined their activities to stimulate the autoi...

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Bibliografische gegevens
Hoofdauteurs: Sheng, Huiming, Hassanali, Saleema, Nugent, Courtney, Wen, Li, Hamilton-Williams, Emma, Dias, Peter, Dai, Yang D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150365/
https://ncbi.nlm.nih.gov/pubmed/21734072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100231
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