Influence of Neuropathology on Convection-Enhanced Delivery in the Rat Hippocampus

Local drug delivery techniques, such as convention-enhanced delivery (CED), are promising novel strategies for delivering therapeutic agents otherwise limited by systemic toxicity and blood-brain-barrier restrictions. CED uses positive pressure to deliver infusate homogeneously into interstitial spa...

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Main Authors: Kantorovich, Svetlana, Astary, Garrett W., King, Michael A., Mareci, Thomas H., Sarntinoranont, Malisa, Carney, Paul R.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3832660/
https://ncbi.nlm.nih.gov/pubmed/24260433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080606
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