A Plant-Produced Pfs25 VLP Malaria Vaccine Candidate Induces Persistent Transmission Blocking Antibodies against Plasmodium falciparum in Immunized Mice

Malaria transmission blocking vaccines (TBVs) are considered an effective means to control and eventually eliminate malaria. The Pfs25 protein, expressed predominantly on the surface of the sexual and sporogonic stages of Plasmodium falciparum including gametes, zygotes and ookinetes, is one of the...

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Main Authors: Jones, R. Mark, Chichester, Jessica A., Mett, Vadim, Jaje, Jennifer, Tottey, Stephen, Manceva, Slobodanka, Casta, Louis J., Gibbs, Sandra K., Musiychuk, Konstantin, Shamloul, Moneim, Norikane, Joey, Mett, Valentina, Streatfield, Stephen J., van de Vegte-Bolmer, Marga, Roeffen, Will, Sauerwein, Robert W., Yusibov, Vidadi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3832600/
https://ncbi.nlm.nih.gov/pubmed/24260245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079538
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