A Plant-Produced Pfs25 VLP Malaria Vaccine Candidate Induces Persistent Transmission Blocking Antibodies against Plasmodium falciparum in Immunized Mice

Malaria transmission blocking vaccines (TBVs) are considered an effective means to control and eventually eliminate malaria. The Pfs25 protein, expressed predominantly on the surface of the sexual and sporogonic stages of Plasmodium falciparum including gametes, zygotes and ookinetes, is one of the...

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Autors principals: Jones, R. Mark, Chichester, Jessica A., Mett, Vadim, Jaje, Jennifer, Tottey, Stephen, Manceva, Slobodanka, Casta, Louis J., Gibbs, Sandra K., Musiychuk, Konstantin, Shamloul, Moneim, Norikane, Joey, Mett, Valentina, Streatfield, Stephen J., van de Vegte-Bolmer, Marga, Roeffen, Will, Sauerwein, Robert W., Yusibov, Vidadi
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3832600/
https://ncbi.nlm.nih.gov/pubmed/24260245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079538
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