Hyperglycemia Enhances the Proliferation of Non-Tumorigenic and Malignant Mammary Epithelial Cells through Increased leptin/IGF1R Signaling and Activation of AKT/mTOR

Obesity and diabetes are associated with increased breast cancer risk and worse disease progression once cancer is diagnosed; however, the exact etiology behind these observations remains to be fully elucidated. Due to the global obesity/diabetes pandemic, it is imperative to understand how these di...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Lopez, Rebecca, Arumugam, Arunkumar, Joseph, Riya, Monga, Kanika, Boopalan, Thiyagarajan, Agullo, Pamela, Gutierrez, Christina, Nandy, Sushmita, Subramani, Ramadevi, de la Rosa, Jose Manuel, Lakshmanaswamy, Rajkumar
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3832533/
https://ncbi.nlm.nih.gov/pubmed/24260287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079708
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