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Discovery of Dihydrochalcone as Potential Lead for Alzheimer’s Disease: In Silico and In Vitro Study
By the virtual screening method we have screened out Dihydrochalcone as a top-lead for the Alzheimer’s disease using the database of about 32364 natural compounds. The binding affinity of this ligand to amyloid beta (A[Image: see text]) fibril has been thoroughly studied by computer simulation and e...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3832475/ https://ncbi.nlm.nih.gov/pubmed/24260164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079151 |
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