Intact microtubules are required for rapid turnover of carboxyl-terminal tyrosine of alpha-tubulin in cell cultures.

In cultured muscle cells the carboxyl-terminal tyrosine of alpha-tubulin was shown to exchange rapidly with free tyrosine. The rapid turnover of this residue was dependent upon the presence of intact microtubules. Half-life determinations were made by two methods: (i) the cells were pulse-labeled in...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Thompson, W C, Deanin, G G, Gordon, M W
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1979
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC383242/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/286314/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.3.1318
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