Reversion to methionine independence in simian virus 40-transformed human and malignant rat fibroblasts is associated with altered ploidy and altered properties of transformation

Many transformed and malignant cells, unlike normal cells, do not grow when methionine in the growth medium is replaced by its immediate precursor homocysteine [Chello, P. & Bertino, J. (1973) Cancer Res. 33, 1898-1904 and Hoffman, R. & Erbe, R. (1976) Proc. Natl. Acad. Sci. USA 73, 1523-1527]. Rare...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Hoffman, Robert M., Jacobsen, Stephen J., Erbe, Richard W.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1979
Schlagworte:	Biological Sciences: Cell Biology
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC383241/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/220612/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.3.1313
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