Gene Amplification and Functional Diversification of Melanocortin 4 Receptor at an Extremely Polymorphic Locus Controlling Sexual Maturation in the Platyfish

In two swordtail species of the genus Xiphophorus, the onset of puberty has been shown to be modulated at the P locus by sequence polymorphism and gene copy-number variation affecting the type 4 melanocortin hormone receptor Mc4r. The system works through the interaction of two allelic types, one en...

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Autores principales: Volff, Jean-Nicolas, Selz, Yvonne, Hoffmann, Carsten, Froschauer, Alexander, Schultheis, Christina, Schmidt, Cornelia, Zhou, Qingchun, Bernhardt, Wolfgang, Hanel, Reinhold, Böhne, Astrid, Brunet, Frédéric, Ségurens, Béatrice, Couloux, Arnaud, Bernard-Samain, Sylvie, Barbe, Valérie, Ozouf-Costaz, Catherine, Galiana, Delphine, Lohse, Martin J., Schartl, Manfred
Formato: Artigo
Lenguaje:Inglês
Publicado: Genetics Society of America 2013
Materias:
Investigations
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3832277/
https://ncbi.nlm.nih.gov/pubmed/24077304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.113.155952
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