Gene Amplification and Functional Diversification of Melanocortin 4 Receptor at an Extremely Polymorphic Locus Controlling Sexual Maturation in the Platyfish

In two swordtail species of the genus Xiphophorus, the onset of puberty has been shown to be modulated at the P locus by sequence polymorphism and gene copy-number variation affecting the type 4 melanocortin hormone receptor Mc4r. The system works through the interaction of two allelic types, one en...

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Autors principals: Volff, Jean-Nicolas, Selz, Yvonne, Hoffmann, Carsten, Froschauer, Alexander, Schultheis, Christina, Schmidt, Cornelia, Zhou, Qingchun, Bernhardt, Wolfgang, Hanel, Reinhold, Böhne, Astrid, Brunet, Frédéric, Ségurens, Béatrice, Couloux, Arnaud, Bernard-Samain, Sylvie, Barbe, Valérie, Ozouf-Costaz, Catherine, Galiana, Delphine, Lohse, Martin J., Schartl, Manfred
Format: Artigo
Idioma:Inglês
Publicat: Genetics Society of America 2013
Matèries:
Investigations
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3832277/
https://ncbi.nlm.nih.gov/pubmed/24077304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.113.155952
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