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New insights into inhibition of human immunodeficiency virus type 1 replication through mutant tRNA(Lys3)

BACKGROUND: Host cellular tRNA(Lys3) is exclusively utilized by human immunodeficiency virus type 1 (HIV-1) as a primer for the replication step of reverse transcription (RTion). Consequently, the priming step of HIV-1 RT constitutes a potential target for anti-HIV-1 intervention. Previous studies i...

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Bibliografiske detaljer
Main Authors: Wu, Chengxiang, Nerurkar, Vivek R, Lu, Yuanan
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3832253/
https://ncbi.nlm.nih.gov/pubmed/24156557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-10-112
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