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New insights into inhibition of human immunodeficiency virus type 1 replication through mutant tRNA(Lys3)
BACKGROUND: Host cellular tRNA(Lys3) is exclusively utilized by human immunodeficiency virus type 1 (HIV-1) as a primer for the replication step of reverse transcription (RTion). Consequently, the priming step of HIV-1 RT constitutes a potential target for anti-HIV-1 intervention. Previous studies i...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3832253/ https://ncbi.nlm.nih.gov/pubmed/24156557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-10-112 |
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