Fibrinogen-specific antibody induces abdominal aortic aneurysm in mice through complement lectin pathway activation

Abdominal aortic aneurysm (AAA) is a common vascular disease associated with high mortality rate due to progressive enlargement and eventual rupture. There is currently no established therapy known to alter the rate of aneurysmal expansion. Thus, understanding the processes that initiate and sustain...

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Autors principals: Zhou, Hui-fang, Yan, Huimin, Bertram, Paula, Hu, Ying, Springer, Luke E., Thompson, Robert W., Curci, John A., Hourcade, Dennis E., Pham, Christine T. N.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2013
Matèries:
PNAS Plus
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3831981/
https://ncbi.nlm.nih.gov/pubmed/24167262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1315512110
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