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Regulation of protein synthesis in rabbit reticulocyte lysates: Additional initiation factor required for formation of ternary complex (eIF-2·GTP·Met-tRNA(f)) and demonstration of inhibitory effect of heme-regulated protein kinase

Heme deficiency in rabbit reticulocytes and their lysates leads to the activation of a heme-regulated translational inhibitor (HRI) which causes the cessation of polypeptide initiation. HRI is a protein kinase that specifically phosphorylates the 38,000-dalton subunit of eukaryotic initiation factor...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Ranu, Rajinder Singh, London, Irving M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1979
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC383192/
https://ncbi.nlm.nih.gov/pubmed/286294
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