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Discovery of GW870086: a potent anti-inflammatory steroid with a unique pharmacological profile

BACKGROUND AND PURPOSE: Glucocorticoids are highly effective therapies for a range of inflammatory diseases. Advances in the understanding of the diverse molecular mechanisms underpinning glucocorticoid action suggest that anti-inflammatory molecules with reduced side effect liabilities can be disco...

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Detalhes bibliográficos
Main Authors: Uings, I J, Needham, D, Matthews, J, Haase, M, Austin, R, Angell, D, Leavens, K, Holt, J, Biggadike, K, Farrow, S N
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3831715/
https://ncbi.nlm.nih.gov/pubmed/23639214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12232
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