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Preclinical evaluation of radiation and perifosine in a genetically and histologically accurate model of brainstem glioma
Brainstem gliomas (BSGs) are a rare group of CNS tumors that arise mostly in children and usually portend a particularly poor prognosis. We report the development of a genetically engineered mouse model of BSG using the RCAS/tv-a system and its implementation in preclinical trials. Using immunohisto...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3831613/ https://ncbi.nlm.nih.gov/pubmed/20197468 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-2503 |
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