Recognition of synthetic glycopeptides by HIV-1 broadly neutralizing antibodies and their unmutated ancestors

Current HIV-1 vaccines elicit strain-specific neutralizing antibodies. Broadly neutralizing antibodies (BnAbs) are not induced by current vaccines, but are found in plasma in ∼20% of HIV-1–infected individuals after several years of infection. One strategy for induction of unfavored antibody respons...

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Autori principali: Alam, S. Munir, Dennison, S. Moses, Aussedat, Baptiste, Vohra, Yusuf, Park, Peter K., Fernández-Tejada, Alberto, Stewart, Shelley, Jaeger, Frederick H., Anasti, Kara, Blinn, Julie H., Kepler, Thomas B., Bonsignori, Mattia, Liao, Hua-Xin, Sodroski, Joseph G., Danishefsky, Samuel J., Haynes, Barton F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2013
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3831483/
https://ncbi.nlm.nih.gov/pubmed/24145434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1317855110
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