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Inhibition of glycogen synthase kinase 3beta activity with lithium prevents and attenuates paclitaxel-induced neuropathic pain

Paclitaxel (taxol) is a first-line chemotherapy-drug used to treat many types of cancers. Neuropathic pain and sensory dysfunction are the major toxicities, which are dose-limiting and significantly reduce the quality of life in patients. Two known critical spinal mechanisms underlying taxol-induced...

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Detalhes bibliográficos
Main Authors: Gao, Mei, Yan, Xisheng, Weng, Han-Rong
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3831340/
https://ncbi.nlm.nih.gov/pubmed/24070631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2013.09.033
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