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Blocking the GABA transporter GAT-1 ameliorates spinal GABAergic disinhibition and neuropathic pain induced by paclitaxel

Paclitaxel is a chemotherapeutic agent widely used for treating carcinomas. Patients receiving paclitaxel often develop neuropathic pain and have a reduced quality of life which hinders the use of this life-saving drug. In this study, we determined the role of GABA transporters in the genesis of pac...

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Detalhes bibliográficos
Publicado no:J Neurochem
Main Authors: Yadav, Ruchi, Yan, Xisheng, Maixner, Dylan W., Gao, Mei, Weng, Han-Rong
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4464967/
https://ncbi.nlm.nih.gov/pubmed/25827582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13103
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