1,3-Bis(2-chloroethyl)-1-nitrosourea enhances the inhibitory effect of Resveratrol on 5-fluorouracil sensitive/resistant colon cancer cells

AIM: To study the mechanism of 5-fluorouracil (5-FU) resistance in colon cancer cells and to develop strategies for overcoming such resistance by combination treatment. METHODS: We established and characterized a 5-FU resistance (5-FU-R) cell line derived from continuous exposure (25 μmol/L) to 5-FU...

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Autores principales: Das, Dipon, Preet, Ranjan, Mohapatra, Purusottam, Satapathy, Shakti Ranjan, Kundu, Chanakya Nath
Formato: Artigo
Lenguaje:Inglês
Publicado: Baishideng Publishing Group Co., Limited 2013
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3831219/
https://ncbi.nlm.nih.gov/pubmed/24259968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v19.i42.7374
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