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Is GDNF beneficial in Parkinson disease?

Glial cell line-derived neurotrophic factor (GDNF) has proved efficacious in treatment of neurodegeneration in toxin-induced models of Parkinson disease (PD), but clinical trials have been equivocal. Do the results of a recent study—suggesting that GDNF is ineffective in an α-synuclein-overexpressio...

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Detalhes bibliográficos
Main Authors: Hoffer, Barry J., Harvey, Brandon
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3830920/
https://ncbi.nlm.nih.gov/pubmed/21931353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrneurol.2011.149
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