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Induction of amplified synthesis and secretion of IgM by fusion of murine 'b lymphoma with myeloma cells.
Murine B lymphoma cultured cell lines bearing membrane IgM and lacking the ability to secrete measurable amounts of IgM were fused with drug-resistant cell lines derived from the IgG2b-producing MPC-11 myeloma. Many of the hybrid clones synthesized and secreted large amounts of IgM, as judged by rad...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1979
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC383092/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/311476/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.2.915 |
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