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Membrane attack complex of complement: generation of high-affinity phospholipid binding sites by fusion of five hydrophilic plasma proteins.

The molecular basis of the membranolytic activity of the membrane attack complex (MAC) of complement was investigated. By using density gradient equilibrium ultracentrifugation, the binding of egg yolk lecithin to the isolated MAC and to its intermediate complexes and precursor proteins was measured...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Podack, E R, Biesecker, G, Müller-Eberhard, H J
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1979
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Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC383086/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/284414/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.2.897
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