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Identification of 7,12-dimethylbenz[a]anthracene metabolites that lead to mutagenesis in mammalian cells
The mutagenicity of 7,12-dimethylbenz[a]-anthracene (DMBA) and 11 of its enzymatically derived metabolites was tested with Chinese hamster V79 cells for identification of mutagenic metabolites. The metabolites consisted of 7-hydroxymethyl-12-methylbenz[a]anthracene, 7-methyl-12-hydroxymethylbenz[a]a...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1979
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC383073/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/106395/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.2.862 |
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