Immunoglobulin heavy chain gene organization in mice: analysis of a myeloma genomic clone containing variable and alpha constant regions.

We have isolated a myeloma genomic DNA clone containing the variable and constant regions of a mouse alpha chain. Restriction enzyme analyses and electron microscopic R loop mapping have demonstrated that the variable region is separated from the constant region by 6.8 kilobases of intervening DNA....

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Main Authors: Early, P W, Davis, M M, Kaback, D B, Davidson, N, Hood, L
Format: Artigo
Sprog:Inglês
Udgivet: 1979
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC383072/
https://ncbi.nlm.nih.gov/pubmed/106394
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