Immunoglobulin heavy chain gene organization in mice: analysis of a myeloma genomic clone containing variable and alpha constant regions.

We have isolated a myeloma genomic DNA clone containing the variable and constant regions of a mouse alpha chain. Restriction enzyme analyses and electron microscopic R loop mapping have demonstrated that the variable region is separated from the constant region by 6.8 kilobases of intervening DNA....

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Early, P W, Davis, M M, Kaback, D B, Davidson, N, Hood, L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1979
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC383072/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/106394/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.2.857
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