Thymosin β4 and its degradation product, Ac-SDKP, are novel reparative factors in renal fibrosis

Previously we found thymosin β4 (Tβ4) is up-regulated in glomerulosclerosis and required for angiotensin II-induced expression of plasminogen activator inhibitor-1 (PAI-1) in glomerular endothelial cells. Tβ4 has beneficial effects in dermal and corneal wound healing and heart disease yet its effect...

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Bibliografiske detaljer
Main Authors: Zuo, Yiqin, Chun, Bongkwon, Potthoff, Sebastian A., Kazi, Naj, Brolin, Tyler J., Orhan, Diclehan, Yang, Hai-Chun, Ma, Li-Jun, Kon, Valentina, Myöhänen, Timo, Rhaleb, Nour-Eddine, Carretero, Oscar A., Fogo, Agnes B.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3830708/
https://ncbi.nlm.nih.gov/pubmed/23739235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2013.209
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