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Thymosin β4 and its degradation product, Ac-SDKP, are novel reparative factors in renal fibrosis
Previously we found thymosin β4 (Tβ4) is up-regulated in glomerulosclerosis and required for angiotensin II-induced expression of plasminogen activator inhibitor-1 (PAI-1) in glomerular endothelial cells. Tβ4 has beneficial effects in dermal and corneal wound healing and heart disease yet its effect...
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| Autors principals: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3830708/ https://ncbi.nlm.nih.gov/pubmed/23739235 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2013.209 |
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