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A serially coupled stationary phase method for the determination of urinary 8-oxo-7,8-dihydro-2′-deoxyguanosine by liquid chromatography ion trap tandem mass spectrometry()

Oxidative attack to DNA is of particular interest since DNA modifications can lead to heritable mutations. The most studied product of DNA oxidation is 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG). While 8-oxodG determination in blood and tissue cells is prone to artifacts, its measurement in urine...

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Detalhes bibliográficos
Main Authors: Rota, Cristina, Cristoni, Simone, Trenti, Tommaso, Cariani, Elisabetta
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3830056/
https://ncbi.nlm.nih.gov/pubmed/24251117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2013.10.001
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