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Initial site of insulin cleavage by insulin protease.

Exposure of insulin to insulin protease (insulinase, EC 3.4.22.11), a degradative enzyme with considerable specificity toward insulin, results in alterations in the properties of the insulin molecule. Limited degradation by the enzyme results in a decrease in the ability of insulin to bind to membra...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Duckworth, W C, Stentz, F B, Heinemann, M, Kitabchi, A E
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1979
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC383003/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/284388/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.2.635
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