Mycophenolic Acid Inhibits Migration and Invasion of Gastric Cancer Cells via Multiple Molecular Pathways

Mycophenolic acid (MPA) is the metabolized product and active element of mycophenolate mofetil (MMF) that has been widely used for the prevention of acute graft rejection. MPA potently inhibits inosine monophosphate dehydrogenase (IMPDH) that is up-regulated in many tumors and MPA is known to inhibi...

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Bibliographic Details
Main Authors: Dun, Boying, Sharma, Ashok, Teng, Yong, Liu, Haitao, Purohit, Sharad, Xu, Heng, Zeng, Lingwen, She, Jin-Xiong
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829969/
https://ncbi.nlm.nih.gov/pubmed/24260584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081702
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